Sunday, July 10, 2016

A big move and a new research group. Join us!

My decision to leave the IMO and Moffitt Radiation Oncology was one of the hardest professional (and personal) choices I've ever made. I've made friends I won't ever be able to replace, and learned lessons I'll never forget. However, for many reasons, including family and professional and personal growth, it is time for me to move on. I'm very lucky to have found a post in my home town at the Cleveland Clinic doing exactly what I want to do. They have hired me be a physician-scientist, to start a research group in the department of Translational Hematology and Oncology Research (yes, they call it THOR - how awesome) studying the evolution of resistance, and to continue my work as a sarcoma radiation oncologist.

I'm lucky to be joined by two brave souls who will begin their DPhils under my co-supervision between Oxford and my lab at the Cleveland Clinic. +Artem Kaznatcheev , a theoretical computer scientists and mathematician (who is also a prolific academic blogger - see his blog TheEgg here) will begin in the department of Computer Science this Michelmas with Peter Jeavons, David Basanta and myself supervising. Artem's thesis project will focus on the evolutionary process, but beyond that we're not sure - we'll find something that piques all of our interests I'm sure. Artem's work with David and I to date has included attempts to bring spatial structure into evolutionary game theory using the Ohtsuki-Nowak transformation. We found, broadly, that game dynamics can change significantly based on local neighborhood size. This finding has, I think, broad implications for understanding spatially heterogeneous tumors using game theoretic methods.





and more recently using time lapse microscopy to quantify competition dynamics in vitro - something I'm presenting a poster on at ECMTB2016 later this week.



There are more ideas than time, in general, when working with Artem, so I'm quite keen to begin this new journey and strengthen the connection between computer science that we began with +Dan Nichol doing his DPhil with Pete Jeavons and +Alexander Anderson - which we kicked off with Dan's evolutionary steering paper.

I'm also very luck to have +Andrew Dhawan joining, who will begin his DPhil in Oncology with Francesca Buffa and Adrian Harris. Andrew's DPhil will be slightly more prescribed, it being under a CRUK studentship. He will be focussing on building a comprehensive map of the transcriptional response to hypoxia in (breast) cancer. Many of you will note that this is reasonably far from my expertise, but I think it will be a great opportunity for me to hone my Next Gen Sequencing chops, and also to inject some theoretical thinking into Oxford Oncology.

Andrew has spent this summer, since he finished medical school in Ontario, Canada at Queen's University School of Medicine, working with me and +Andriy Marusyk on collateral sensitivity in non-small cell lung cancer. He is attending a summer school (sponsore by the Cancer Research UK coincidentally) on ecology and evolution in cancer - annoying scheduled the same week as ECMTB. He'll be presenting the following poster there:


On another random note: it turns out, unbeknownst to any of us, Andrew and Artem did their undergrad at the same institution, in the same department! They both went to the 'MIT of Canada' in Waterloo. Small world.

Anyways, I am immensely looking forward to this move - the next few weeks will see me at ECMTB, then home to Tampa for one day, and then the move Cleveland, where I start August 1st. I am also looking for someone interested in joining the team as a post-doc who wants to work with us to make a difference in patient's lives through the study of evolution in cancer (or bacteria) with primarily mathematical methods.

If you're coming to ECMTB, look me up!


8 comments:

  1. I am so happy to be finally cured of herpes simplex virus  by herbalist Razor,Ever since i was diagnosed with the virus i have been using medical drugs to suppress it, i later realized it was causing more damage to my health than the virus,i opted for herbs and got to find out about the great work herbalist Doctor razor have been doing with his herbal remedy. i contacted him and he promised to help me get rid of it,after 4 days i received a package fro the delivery service and it was from the doctor who sent me the herbal treatment in Dallas,Texas USA, And he instructed me on how i was going too take in for the 18 days. After completing the dosage he told e to go for a medical checkup and when i did the doctors conducted some test on me but they were stunned that my status was now negative,they conducted several test on me to be sure. i even went to Medical City Dallas Hospital, where they conducted another test and it was still negative. I am so grateful to you herbal doctor razor , God will continue to prosper you,i pray the world gets to know about you and your herbal exploits. Reach him on his email : drrazorherbalhome@gmail.com Whatsapp/Call his cell phone on +2349065420442. PLEASE SHARE , SO THE WORLD CAN GET TO KNOW ABOUT HIM

    ReplyDelete
    Replies
    1. To know more about Chief Dr Lucky you can visit his website (https://chiefdrluckyherbaltherapy.wordpress.com/)
       
       A friend that suffered from Herpes and was cure with the help of this great herbal doctor Chief Lucky so i decided to contact him for help in getting rid of my families genital herpes virus 1/2 which i did and all i was told to provide was just some useful information and some materials used in preparation of the natural cure and that i did and now i am the happiest person on earth because i am writing this testimony of mine with joy and happiness in my heart to the whole world to know that natural remedy is real because i am a living testimony of Chief Lucky traditional herbal cure and i want you all to contact Chief Lucky via his email: chiefdrlucky@gmail.com or WhatsApp him +2348132777335 am sure he will help you too.

      Delete
  2. I am so happy to be finally cured of herpes simplex virus  by herbalist Razor,Ever since i was diagnosed with the virus i have been using medical drugs to suppress it, i later realized it was causing more damage to my health than the virus,i opted for herbs and got to find out about the great work herbalist Doctor razor have been doing with his herbal remedy. i contacted him and he promised to help me get rid of it,after 4 days i received a package fro the delivery service and it was from the doctor who sent me the herbal treatment in Dallas,Texas USA, And he instructed me on how i was going too take in for the 18 days. After completing the dosage he told e to go for a medical checkup and when i did the doctors conducted some test on me but they were stunned that my status was now negative,they conducted several test on me to be sure. i even went to Medical City Dallas Hospital, where they conducted another test and it was still negative. I am so grateful to you herbal doctor razor , God will continue to prosper you,i pray the world gets to know about you and your herbal exploits. Reach him on his email : drrazorherbalhome@gmail.com Whatsapp/Call his cell phone on +2349065420442. PLEASE SHARE , SO THE WORLD CAN GET TO KNOW ABOUT HIM

    ReplyDelete
  3. Its a miracle that I am alive today. I encounter HERPES SIMPLEX VIRUS (HSV1&2) for good four (4) years, six (6) months and Ten (10) days with my calculations, before I met Doctor Razor. I am from New York City ,NY USA,I was affected with herpes simplex virus.  Herpes is a viral infection cause by the Herpes simplex virus, marked by painful, watery blister in the skin or mucus membrane or on the genitals. This was what I suffered for over 4 years. I have visited so many hospitals in Houston for treatment but no improvement. I met Doctor Razor on the internet while I was searching for herpes cure,I read some testimonies about his work. I decided to give  his herbal medication a trial, which have now become a testimony in my life. i am so grateful to God almighty for sending doctor Razor my way when i thought all hope was lost. You too can get cured of herpes Simplex virus, if i could overcome it. Reach out to doctor razor via his clinic email : drrazorherbalhome@gmail.com. Whatsapp his cell phone ON +2349065420442

    ReplyDelete
  4. HOW I WAS ABLE TO FLUSH OUT THE HERPES VIRUS WITH THE HELP OF DR. KHAM NATURAL PRODUCT, HIS EMAIL dr.khamcaregiver@gmail.com. I was diagnosed with Herpes a year ago. It’s the worst thing that’s ever happened to me and  I feel like my life is over. Living with constant pain is something no one should have to go through, Herpes has also had a huge impact on my sleep . Since being diagnosed I’ve fallen so far into depression I see no way out because i have been to different hospital. I’m taking a high dose of antidepressants, as well as sedatives and sleeping-pills. I don’t know how I’ll ever accept that this is my life now…I keep asking why me because know changes? But I guess reading your testimony really made me feel happy because i believe what i had from people out there who you also help to cure the herpes virus, and i believe so much with your herbal medicine i am going to be out of this bad situation like others you also help before, what we i have done if not for the herbal medicine that i requested for that was able to flush out the bad virus that was making me go crazy. people out there how will i thank this man called DR. KHAM, i will advice you to email him direct if you have disease like herpes etc. dr.khamcaregiver@gmail.com or whatsapp him +2348159922297

    ReplyDelete
  5. Before people said there is no cure for herpes virus but today many people have now believe that there is a cure,herpes virus can be cured through Africans roots and herbs, Dr.chala he is the one of the great herbal doctor in Africa and he has the cure on this virus last month he share his herbal medicine in some medical hospital and now he is well recognize as one of the best in Africa, you don’t have to be sad any more or share your tears any more on this virus when the cure have already be find by Dr.Chala email him on dr.chalaherbalhome@gmail.com or https://
    drchalaherbalhome.godaddysites.com or https://mywa.link/dr.chalaherbalhome

    ReplyDelete
  6. HERBAL DR EMU WHO PREPARE HERBAL MEDICINE TO CURE ALL KINDS OF DISEASES INCLUDING HERPES DISEASE.   
     I have been battling this Herpes disease for almost 3 years now....I tried all possible means to get cure from my Herpes Disease but all to be in vain until i saw a post in a health forum about a herbal Dr Emu who prepare herbal medicine to cure all kind of diseases including Herpes Disease, at first i doubted if it was real but decided to give it a try...when i contact Dr Emu via his email (emutemple@gmail.com)  write him and reply me explain how the process work so after ordering for the medicine I got it within 3/4 working days through DHL Delivery and I took it according to the way Dr Emu instructed, I was so happy after 2 week I took the medicine there was very big change in my health when I was done with the process I go for test, I found out I am negative...Herpes patients should also get in touch with this herbalist Dr Emu to get rid of these Herpes Virus forever his whatsapp number +2347012841542. Website: https://emutemple.wordpress.com/ 

    ReplyDelete
  7. I have been a herpes carrier for 2 years and I tried every possible means
    of curing but all of no useful until I saw a health promotion on a
    herbalist from Africa who prepares herbal medicines to cure all sorts of
    diseases including cancer and many others sickness, I first doubted It was
    not true but decided to try, when I contacted this herbal physician via his
    email, I purchased herpes herbal medicine and received it within 7 days
    and used it as prescribed, I tested negative within 3 weeks of use, do not
    lose hope to contact him early If you need help, am convinced he can help you too,
    He is also special in curing 1.
    HIV/AIDS 2. HERPES 3. CANCER 4. ALS 5. HEPATITIS B 6. DIABETES 7. HUMAN
    PAPILLOMAVIRUS DISEASE(HPV) 8. ALZHEIMER 9. LUPUS (Lupus Vulgaris or Lupus Eratosthenes)ETC,,,,,, You can also visit his website:
    http://drchalaherbalhome.godaddysites.com
     email him on dr.chalaherbalhome@gmail.com

    ReplyDelete