Wednesday, December 9, 2020

Introducing our new Theory Division YouTube channel!

It turns out managing a blog is really hard during the assistant professor years.  As in, I've posted on average once a year since I started this job...  

So -- in hopes of doing better, we're going to start something new!

Each week in Theory Division we have lab meeting (which in itself is worthy of a post -- turns out no one teaches you how to run these, and how to best do it changes a LOT depending on the size of your lab), and we also have a one hour slot separately for either journal club, or for a long form research talk. Given the pandemic, these have been done via Zoom, and so have been recorded.  So, what we are going to do is, for each long form research talk we will post the recording to our new youtube channel, along with a short textual abstract here on the blog with a link to the talk.



I'll start things off!

Just yesterday, my colleagues and I had a paper come out in the Journal of Thoracic Oncology: 

Personalizing Radiotherapy Prescription Dose Using Genomic Markers of Radiosensitivity and Normal Tissue Toxicity in Non-Small Cell Lung Cancer

This paper was the subject of my Peter Canham lecture in biophysics at Western University this year -- and we have ported this talk to be our first in the channel -- head over to the channel to watch/subscribe!

Click here to watch this talk on our new channel.

In this talk I discuss some of the frustration I feel as a radiation oncologist that our field has not yet entered the era of personalized medicine -- that is, each cancer patient doesn't have their radiation therapy (DOSE!) tailored to their tumor's genomic profile. Certainly, each prescription is physically personalized (geometrically), but biologically personalized dosing is not yet standard of care. Starting with the beautiful opening (to use a chess analogy) starting with a breakthrough creation of a Radiation Sensitivity Index (RSI) which linked canonical ideas of SF2 in radiation biology to genomics, by my friend and mentor Javier Torres-Roca, he and I and our colleagues have slowly and methodically moved through the middle game, setting the stage for a relationship to dose, which we outlined in our article: A genome-based model for adjusting radiotherapy dose (GARD): a retrospective, cohort-based study

We then (I hope) end the middle game with this paper from yesterday (see above), where we use information about what dose is needed to optimize a given patient's tumor control to then make inferences about OVER and UNDER treatment -- and using a novel combined model of TCP and NTCP, determine how much we could make radiation therapy better right now.

So - head on over to our youtube channel, watch the video, let me know what you think!  And subscribe to see future talks in our lab!

9 comments:

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    ReplyDelete
    Replies
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  5. I'm very excited to inform everyone that I'm completely cured from my HSV 1&2 recently. I have used Oregano oil, Coconut oil, Acyclovir, Val acyclovir, Famciclovir , and some other products and it's really help during my outbreaks but I totally got cured from my HSV 2 with a strong and active herbal medicine ordered from a powerful herbalist and it completely fought the virus from my nervous system and I was tested negative after three weeks of usage. I'm here to let y'all know that HSV 1& 2 has a complete cure, I got rid of mine with the help of Dr Moses Buba and his herbal exploit, AFTER I engage with other wrong doctors. Contact him via email: buba.herbalmiraclemedicine@gmail.com or Call/WhatsApp him at +2349060529305
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  6. To know more about Chief Dr Lucky you can visit his website (https://chiefdrluckyherbaltherapy.wordpress.com/)
     
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    ReplyDelete
  7. DR. OSATO`S CURE FOR HERPES1&2 - A NATURAL WAY TO GET HERPES1&2 CURED. If you have been looking for ways to naturally get rid of the herpes simplex virus from your body totally, then you are welcome to read further. Let's face reality here, you have tried so many counter drugs and you are confused, weak and angry because nothing seems to work. Good News For you my friend.... Yes, I came with a good news that will liberate you from the pains and stress of herpes outbreak, you will get total cure from this virus using Dr. Osato Herbal Methodology. Who is Dr. Osato? You may ask. Dr. Osato is a herbalist and a naturalist. He researched and identified some herbs and established a unique methodology to healing the human body using Herbal medicine that was confidently entrenched in his over 30 years of experience. According to him, he has the cure for so many diseases/virus like GENITAL HERPES, HIV, DIABETES, CANCER, HPV, HSV1&2, GENITAL WART, SHINGLES, VIRGINAL INFECTION and so many more. You can reach Dr Osato on his email: osatoherbalcure@gmail.com or WhatsApp +2347051705853. You can also contact him through his website: https://osatoherbalcure.wordpress.com or message him easily on his facebook page: https://www.facebook.com/Dr-Osato-Herbal-Cure-106002928040920/. I am using this medium to inform everyone how to get treated of herpes using Dr Osato recommended Herbal methodology.

    ReplyDelete