Just a quick note, as +Andrew Dhawan has covered most of it. Just wanted to share some excitement about a new preprint from our group which you can find here:
https://www.biorxiv.org/content/early/2018/03/31/292029
A full 'Story behind the preprint' to be found on Andrew's blog: Tabula Rasa
But to whet you interest, here is a little tweet thread I made, and you can see some of the conversation - even pointing us to some good references we missed, thanks Marc!